Since the update from 1.x to 2.2, there have been many problems, such as this problem (Instant Run requires that the platform corresponding to your target device (Android 6.0 (Marshmollow)) is installed), until recently there is time to solve:

It seems that this is because the SDK version of the external device you are connected to does not have a corresponding version on the computer, so the solution is to install the corresponding SDK according to the missing version prompted: